I am a computational biophysicist working as a research fellow in John Christodoulou group at UCL, where I study co-translational protein folding using mainly multi-scale molecular dynamics simulations. Through my research, I have developed all-atom and coarse-grained molecular dynamics simulations of ribosomal nascent chain complexes with structural restraints based on experimental data (mainly from NMR and cryo-EM). For cryo-EM maps I have developed method based on Bayesian inference to re-weight structural ensemble obtained from simulations so it better captures heterogenity present in cryo-EM data. Using these methods I have characterised interactions between the nascent chain and the ribosome for unfolded and folded nascent chains as well as folding intermediate state on the ribosome.
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PhD in Bioinformatics and Biophysics, 2013
University of Warsaw, Warsaw, Poland
MSc in Biophysics, 2008
Jagiellonian University, Cracow, Poland
Python, Bash, AWK, Tcl, R, git, LaTeX
GROMACS, NAMD, PLUMED
Polish(native), English(fluent), Russian(basic), German(basic)