Tomek Włodarski

Tomek Włodarski

Research Fellow

Department of Structural and Molecular Biology

University College London

About me

I am a computational biophysicist working as a research fellow in John Christodoulou group at UCL, where I study co-translational protein folding using mainly multi-scale molecular dynamics simulations. Through my research, I have developed all-atom and coarse-grained molecular dynamics simulations of ribosomal nascent chain complexes with structural restraints based on experimental data (mainly from NMR and cryo-EM). For cryo-EM maps I have developed method based on Bayesian inference to re-weight structural ensemble obtained from simulations so it better captures heterogenity present in cryo-EM data. Using these methods I have characterised interactions between the nascent chain and the ribosome for unfolded and folded nascent chains as well as folding intermediate state on the ribosome.

Download my resumé.

  • protein co-translational folding
  • molecular dynamics simulations
  • integrative structural biology
  • structural bioinformatics
  • protein design
  • machine learning
  • PhD in Bioinformatics and Biophysics, 2013

    University of Warsaw, Warsaw, Poland

  • MSc in Biophysics, 2008

    Jagiellonian University, Cracow, Poland


Python, Bash, AWK, Tcl, R, git, LaTeX

MD simulations codes



Polish(native), English(fluent), Russian(basic), German(basic)